Doxycycline and Gentamicin Sulphate Veterinary Oral Powder
COMPOSITION: Each gm contains:
Doxycycline Hyclate BP Equivalent to Doxycycline : 200 mg
Gentamicin Sulphate BP : 200 mg
Excipients : Q.S.
DESCRIPTION:
Doxycycline is a semi-synthetic broad–spectrum antibiotic from
tetracycline class, active against both aerobic and anaerobic rampositive
and Gram-negative bacteria: Staphylococcus spp., Haemophilus spp.,
E. coli, Pasteurella spp., Bacillus anthracis, some Clostridium spp,
Actinomyces spp., Brucella spp., Salmonella spp., also against
Mycoplasma spp., Ricketsia spp. and Chlamydia spp. Gentamycin is a
bactericidal aminoglycoside active against most gramnegative aerobic
rods and some gram-positive bacteria: Enterobacter spp., E. coli,
Salmonella spp., Brucella spp., Haemophilus spp., Pasteurella spp., most
strains of Treponema spp. strains etc. When combined, doxycycline and
gentamicin can act synergistically.
INDICATIONS:
Treatment of infections caused by microorganisms susceptible to
doxycycline and/or gentamycin in calves, sheep, goats, pigs, poultry and
horses. The product is especially indicated in gastrointestinal and
respiratory tract infections. Large animals: pasteurelosis, actynobacilosis,
neonatal collibacilosis, brucellosis, pneumonia, enteritis, anaplasmosis,
mycoplasmosis, proliferative adenomatosis, septicemia etc. Poultry:
colibacilosis, psittacosis, chronic respiratory diseases (synovitis, coryza),
pasteurellosis (fowl cholera) etc
CONTRAINDICATIONS:
Hypersensitivity to aminoglycosides and/or tetracyclines. Animals with
impaired renal or hepatic function, animals with vestibular or ear
dysfunctions or animals with an active microbial digestion.
DOSAGE:
For oral administration in drinking water or via feed.
Calves, sheep, goats and horses: 2.5 gm per 100 kg body weight, once
or twice daily, as required for 3-5 days.
Swine: 2.5 gm per 100 kg body weight, once or twice daily, as required for 3-5 days
Poultry: 375 gm per 1000 liters of drinking water, daily, for 3-5 days.
NOTE: Medicated feed should be used immediately.
SIDE EFFECTS: Hyper sensibility reactions,
rarely gastrointestinal disturbances. Tetracyclines
(doxycycline) may cause discoloration of bones and teeth to a yellow, brown or grey colour. In
extreme overdosages nephrotoxicity, ototoxicity or neurotoxicity symptoms could occur.
WITHDRAWL PERIOD:
(poultry)
and laying hens producing eggs for human consumption.
PACKINGS:100 gm, 250 gm, 500 gm, 1Kg, 5 kg,
10 Kg, 25 Kg & 50 Kg.
